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The Human Phenotype Project


THE WORLD'S DEEPEST PHENOTYPE MULTI-OMIC STUDY

OUR MISSION IS TO IMPROVE HUMAN HEALTH

By collecting & sharing the world’s deepest phenotype multi-omic datasets

100,000 Participants, Globally, Over 25 Years

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The Human Phenotype Project is a landmark initiative, powered by Pheno.AI, that set out to deeply profile hundreds of thousands of participants from around the world, in an effort to unlock the information researchers need to improve human health.


We are profiling participants from multiple countries at the unprecedented depth & consistency required to discover the next breakthroughs across healthcare, life sciences & pharma industries.



DIVERSITY

Now scaling to >100 000 participants from around the globe


LONGITUDINAL

Collecting data from participants annually for a period of 25 years


DEPTH

Deep phenotype multi-omic characterization for every participant profiled



RESEARCH READY

Data cleaned & documented ready for your research

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For Researchers

The Human Phenotype Project data is available to universities and other research institutions who wish to conduct human health research

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Build Your Cohort

Build your cohort faster and cheaper than ever before. Cohort-in-a-Box is an end-to-end standardized solution that enables researchers to join the Human Phenotype Project by profiling their own multi-omic longitudinal cohort

Publications

Phenome-wide associations of human aging uncover sex-specific dynamics


Identification of gut microbiome features associated with host metabolic health in a large population-based cohort

From Glucose Patterns to Health Outcomes: A Generalizable Foundation Model for Continuous Glucose Monitor Data Analysis

Continuous glucose monitoring and intrapersonal variability in fasting glucose

Unveiling Associations Between Retinal Microvascular Architecture and Phenotypes Across Thousands of Healthy Subjects

Genome-wide association studies and polygenic risk score phenome-wide association studies across complex phenotypes in the human phenotype project

A Multimodal Dataset of 21,412 Recorded Nights for Sleep and Respiratory Research


Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients

An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

Clinical efficacy of fecal microbial transplantationtreatment in adults with moderate‐to‐severe atopicdermatitis

Personalized Postprandial Glucose Response–Targeting Diet Versus Mediterranean Diet for Glycemic Control in Prediabetes

Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota

10 K: a large‐scale prospective longitudinal study in Israel

Potential role of indolelactate and butyrate in multiple sclerosis revealed by integrated microbiome-metabolome analysis

A reference map of potential determinants for the human serum metabolome

Rich data sets could end costly drug discovery

Axes of a revolution: challenges and promises of big data in healthcare

Sub-genomic variation in the gut microbiome associates with host metabolic health

Environment dominates over host genetics in shaping human gut microbiota

Persistent microbiome alterations modulate the rate of post-dieting weight regain

Personalized Nutrition by Prediction of Glycemic Responses

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

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Contact us

Thank you for contacting Pheno.AI.

For more information, please, email us at info@humanphenotypeproject.org